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Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually
A UCLA study links faster brain aging to specific gut bacteria and chemical byproducts, with older-looking brains also associated with poorer memory, focus, and mood. The findings suggest that biological signs of brain aging may appear decades before obvious symptoms and could ev
High-risk MDS stem cells appear to have an unexpected “energy addiction,” relying far more heavily than healthy blood-forming cells on a molecule called NAD. Disrupting this energy pathway selectively weakened the cancer-driving cells, revealing a potential new target for treatme
A common mistake during blood pressure checks could make readings appear substantially higher than they really are. Johns Hopkins researchers found that leaving the arm unsupported can raise systolic readings by about 6.5 mmHg, potentially affecting a hypertension diagnosis.
A review of more than 265,000 people found that cannabis use was associated with higher rates of both committing violence and becoming a victim of it. The researchers say the link is significant but does not prove cannabis itself is the cause.
A massive MRI study found that Alzheimer’s disease, mild cognitive impairment, psychiatric disorders, and addiction are associated with distinct patterns of accelerated brain aging. The strongest effects appeared in Alzheimer’s and mild cognitive impairment, while ADHD and autism
People with diabetes reported better quality of life after days when their glucose stayed largely within a healthy range, even when levels fluctuated more than usual. The unexpected finding suggests that pursuing extremely tight glucose control may sometimes come with a hidden li
Scientists resurrected antimicrobial peptides from mammals that lived millions of years ago and found that some were more potent against drug-resistant bacteria than modern human versions. These evolutionary relics could provide new clues for designing treatments as antibiotic re
Scientists discovered rare flavoalkaloids in Cannabis leaves for the first time, along with dozens of other phenolic compounds that had never been reported in the plant. The findings suggest that Cannabis leaves, often discarded as waste, may contain a surprisingly rich source of
A major analysis suggests Phelan-McDermid syndrome, a genetic disorder closely linked to autism, may affect about 1 in 7,300 people and more than 45,000 Americans. Researchers warn that thousands of cases may remain hidden because genetic testing is often not performed, even as t
A topical drug that removes aging, damaged cells helped older mice heal skin wounds significantly faster. The treatment appeared to reactivate repair pathways involved in inflammation, collagen production, and new blood vessel growth.
A minimally invasive procedure called genicular artery embolization could offer a new middle ground between conservative treatments and knee replacement for osteoarthritis. By blocking tiny blood vessels associated with inflammation, GAE can significantly reduce pain, with some p
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually
A new nanoparticle therapy reduced lung tumors in mice while also targeting cachexia, the severe muscle wasting that can accompany cancer. By delivering follistatin mRNA directly to tumors, the approach could eventually offer a way to fight both the disease and one of its most da
Scientists have discovered a human gene with a remarkable double life: it appears to play an important role in brain cells while still retaining the ability to jump around the genome. Called BC200, the gene evolved millions of years ago from a mobile piece of DNA known as a trans
Cancer immunotherapy can lose its punch when tumor-fighting T cells become exhausted, but researchers may have found a way to keep them going longer. Scientists at Memorial Sloan Kettering Cancer Center identified a signaling molecule called MEK that can push T cells to burn thro
Scientists have discovered that E-cadherin, a protein best known as the “glue” holding cells and tissues together, has a surprising second job: helping epithelial cells swallow nearby dead cells. Using live zebrafish and mouse embryos, researchers found that cells can dramaticall
Researchers found that just 20 minutes of comfortable walking can rapidly stimulate the gut. Within one to two minutes after exercise, bowel sounds became stronger, more frequent, and lasted longer, suggesting increased intestinal movement. The boost was brief, fading within a fe
A UCLA study links faster brain aging to specific gut bacteria and chemical byproducts, with older-looking brains also associated with poorer memory, focus, and mood. The findings suggest that biological signs of brain aging may appear decades before obvious symptoms and could ev
High-dose vitamin B3 is showing intriguing early promise as an addition to standard glioblastoma treatment, with 82% of patients in a small trial remaining progression-free after six months. Researchers believe niacin may help revive immune cells suppressed by the cancer, but lar
A vitamin D analog may help break down pancreatic cancer’s protective defenses, potentially making tumors more vulnerable to chemotherapy and immune attack. A small clinical trial found encouraging responses, especially in patients whose tumors had high levels of the vitamin D re
A two-year randomized clinical trial involving 493 adults with overweight or obesity found that diet soft drinks were essentially as effective as water for long-term weight loss and weight maintenance. Participants drinking beverages sweetened with aspartame, acesulfame-K, or suc
Scientists have identified an enzyme that may act as a natural defense against the worsening of fatty liver disease, which affects an estimated 100 million Americans. The enzyme, called UBE2N, helps liver cells clear away damaged mitochondria and break down fat, potentially preve
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and metabolism that could eventually lead to new approaches for metabolic disorders and
